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Brain connectivity and psychiatric comorbidity in adolescents with Internet gaming disorder

Brain connectivity and psychiatric comorbidity in adolescents with Internet gaming disorder

This study measured brain functional connectivity in 151 adolescents with and without compulsive video game playing. Subjects with Internet gaming disorder showed higher connectivity between sensory cortex, salience network, and dorsal attention network, possibly adaptive training effects of gaming, but also increased connectivity between default mode and executive networks, which may relate to ps
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Genetic and pharmacological manipulation of glyoxalase 1 regulates voluntary ethanol consumption in mice

Abstract
Previous studies have identified an association between the gene glyoxalase 1 (Glo1) and anxiety‐like behavior in mice and have shown that the substrate of GLO1, methylglyoxal, is a competitive partial agonist at GABAA receptors. Given the well‐established role of GABAA receptors in the behavioral effects of ethanol (EtOH), we investigated the role of Glo1 in voluntary EtOH consumptio
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Mental health and substance use in an urban First Nations population in Hamilton, Ontario.

CONCLUSION: First Nations adults living in Hamilton experience a disproportionate burden of mental health and addictions. By working in partnership with urban Aboriginal organizations, it is possible to produce policy- and service-relevant data and address the current deficiency in appropriate mental health and substance use services for urban Aboriginal people.
PMID: 26680428 [PubMed – in pro
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What Matters Most to You?

What matters most to you? The Practice: Remember the big things. Why? In every life, reminders arrive about what’s really important. I’ve recently received one myself, in a form that’s already come to countless people and will come to countless more: news of a potentially serious health problem. My semi-annual dermatology mole check turned up a localized melanoma cancer in my ear that will need to
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The Science Behind Charles Dickens’ A Christmas Carol

First published in 1843, A Christmas Carol is a timeless story that we have cherished ever since, especially during the holidays. The tale by Charles Dickens has been adapted and re-adapted, modified and satired, with such frequency that we may not even recognize it in all its forms.So why is it so timeless? Why has it had such a lasting cultural impact? What is it that so strongly connects with u
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