Glucose Addiction in Cancer Therapy: Advances and Drawbacks.

Authors: Granja S, Pinheiro C, Reis RM, Martinho O, Baltazar F
Abstract
While normal differentiated cells primarily use mitochondrial respiration to generate the required energy for cellular processes, most cancer cells rely on glycolysis, even in sufficient oxygen conditions. This phenomenon is known as the “Warburg effect” or aerobic glycolysis and the metabolic reprogramming of cancer c
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CONCLUSIONS: Alcohol-related cirrhosis and alcohol-related liver disorders will be the major cause of liver disease in the coming decades. There is an urgent need to allocate resources aimed toward understanding the pathogenesis of the disease and its complications so that effective therapies can be developed.
PMID: 26500036 [PubMed – in process] (Source: Alcoholism, Clinical and Experimental
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Muslim majority countries have adopted a range of civil alcohol policies in recent decades. There is a pressing need for better data and to support Muslim majority countries in alcohol policy development. Lessons from Muslim majority countries can help to inform other parts of the world. Al-Ansari, B. , Thow, A.-M. , Day, C. A. , and Conigrave, K. M. (2015 ) Extent of alcohol prohibition in civil
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ConclusionsCoolmine Therapeutic Community was established when drug treatment services in Ireland were in their infancy, and its changing fortunes over subsequent decades reflected changing perceptions of what constitutes appropriate addiction treatment—and in particular the role to be played by former addicts within addiction treatment systems—as well as changing perceptions of funding relati
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ConclusionsWe interpret the effect sizes found in this review to indicate modest yet beneficial and potentially meaningful effects of these interventions, given their brevity and low cost. This interpretation is consistent with other reviews on brief, MI‐based interventions and brief interventions more generally. We therefore encourage the field to re‐open dialogue about the clinical importanc
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