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BC mulls framework for expanded heroin-assisted treatment

BC mulls framework for expanded heroin-assisted treatment

Prescription heroin, a last-resort treatment for severe addiction currently restricted to only one clinic in all of North America, could one day be …
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Risk of heavy drinking among sexual minority adolescents: Indirect pathways through sexual orientation‐related victimization and affiliation with substance‐using peers

ConclusionsSexual minority adolescents in the US appear to exhibit increased heavy episodic drinking via an indirect socialization pathway including affiliations with substance‐using peers and a concurrent indirect pathway involving sexual minority‐related victimization. The pathways appear to operate similarly for boys and girls. This article is protected by copyright. All rights reserved. (S
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Hedgehog pathway maintains cell survival under stress conditions, and drives drug resistance in lung adenocarcinoma.

Hedgehog (HH) pathway plays an important role in embryonic development, but is largely inactive in adult except for tissue repair. Aberrant activation of HH pathway has been found in a variety of cancer types. In non-small cell lung cancer, however, the role and importance of HH pathway remain controversial. In the current study, we found that HH pathway was maintained in low activity in lung ade
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Off-Target Drug Effects Resulting in Altered Gene Expression Events with Epigenetic and “Quasi-Epigenetic” Origins

Publication date: Available online 26 March 2016 Source:Pharmacological Research Author(s): Stephen J. Anderson, Kristina M. Feye, Garrett R. Schmidt-McCormack, Emir Malovic, Gregory S.A. Mlynarczyk, Patricia Izbicki, Larissa F. Arnold, Matthew A. Jefferson, Bierlein M. de la Rosa, Rita F. Wehrman, KC Luna, Hilary Z. Hu, Naveen C. Kondru, Michael D. Kleinhenz, Joe S. Smith, Sirees
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The mesolimbic system and eating addiction: what sugar does and does not do

Publication date: June 2016 Source:Current Opinion in Behavioral Sciences, Volume 9 Author(s): Johannes W De Jong, Louk JMJ Vanderschuren, Roger AH Adan Obesity and obesity-related disorders are a major threat to public health. It has been suggested that food addiction is a valid clinical concept and that food addiction is a contributing factor to the obesity epidemic. Research involving rest
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