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Hedgehog pathway maintains cell survival under stress conditions, and drives drug resistance in lung adenocarcinoma.

Hedgehog pathway maintains cell survival under stress conditions, and drives drug resistance in lung adenocarcinoma.

In conclusion, this study showed that HH pathway is a survival signaling that drives LAC cell growth under stress conditions, and HHIP is a key regulator to block the induction of HH pathway. Targeting the HH pathway through inhibitors or HHIP thus holds promise to address EGFR-TKI resistance in LAC in clinic.
PMID: 27015549 [PubMed – as supplied by publisher] (Source: Oncotarget)MedWorm Spons
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To Help Newborns Dependent On Opioids, Hospitals Rethink Mom’s Role

Carolyn Rossi, a registered nurse at the Hospital of Central Connecticut, says the opioid epidemic has required nurses who used to specialize in care for infants gain insights into caring for addicted mothers, as well. Rusty Kimball/Courtesy of Hartford HealthCare hide caption Carolyn Rossi, a registered nurse at the Hospital of Central Connecticut, says the opioid epidemic has required nurse
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The Social Media Disorder Scale: Validity and psychometric properties

Publication date: August 2016 Source:Computers in Human Behavior, Volume 61 Author(s): Regina J.J.M. van den Eijnden, Jeroen S. Lemmens, Patti M. Valkenburg There is growing evidence that social media addiction is an evolving problem, particularly among adolescents. However, the absence of an instrument measuring social media addiction hinders further development of the research field. The pr
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A pilot randomized clinical trial of an intervention to reduce overdose risk behaviors among emergency department patients at risk for prescription opioid overdose

(Source: Drug and Alcohol Dependence)
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Characterization of comorbid PTSD in treatment-seeking alcohol dependent inpatients: Severity and personality trait differences

(Source: Drug and Alcohol Dependence)
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