Impact of Impulse Control Disorders on Sleep-Wake Regulation in Parkinson's Disease.

Authors: Djamshidian A, Poewe W, Högl B
Abstract
Sleep disturbances are common in patients with Parkinson’s disease (PD) and are even more prevalent in patients with behavioural addictions, such as pathological gambling, compulsive sexual behaviour, compulsive buying, binge eating, punding, and the compulsive use of dopamine replacement therapy. An overview of the relationship between the
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Authors: Dupont T, Yang S, Patel J, Hatzi K, Malik A, Tam W, Martin P, Leonard J, Melnick A, Cerchietti L
Abstract
The BCL6 oncogene plays a crucial role in sustaining diffuse large B-cell lymphomas (DLBCL) through transcriptional repression of key checkpoint genes. BCL6-targeted therapy kills lymphoma cells by releasing these checkpoints. However BCL6 also directly represses several DLBCL
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Abstract
Aversive events rapidly and potently excite certain dopamine neurons in the ventral tegmental area (VTA), promoting phasic increases in the medial prefrontal cortex and nucleus accumbens. This is in apparent contradiction to a wealth of literature demonstrating that most VTA dopamine neurons are strongly activated by reward and reward-predictive cues while inhibited by aversive s
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Wittenberg, E. , Bray, J. W. , Aden, B. , Gebremariam, A. , Nosyk, B. , and Schackman, B. R. (2015 ) Measuring benefits of opioid misuse treatment for economic evaluation: health-related quality of life of opioid-dependent individuals and their spouses as assessed by a sample of the US population . Addiction , doi: 10.1111/add.13219. Center for Health Decision Science, Harvard T.H. Chan School of
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Despite widespread implementation of compulsory treatment modalities for drug dependence, there has been no systematic evaluation of the scientific evidence on the effectiveness of compulsory drug treatment. (Source: International Journal of Drug Policy)MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.
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