Cocaine and opioid co-use is a notable public health concern, but little is known about correlates of this behavior. Most prior findings come from treatment samples and concern cocaine and heroin. Findings from a nationally representative sample involving primarily prescription opioid misuse would expand knowledge. Past-12-month cocaine and/or opioid users in Wave 1 of the National Epidemiologic
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In the UK, almost a quarter (24.8 per cent) of adults are clinically obese and a 61.7 per cent are either overweight or obese. While sugar is not the singular cause, it certainly plays a significant role by wreaking havoc with our appetite and digestive system and flooding the body with ‘empty calories’. Health officials, now well aware of the long-term dangers of excess c
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What’s more harmful to patients being treated for drug or alcohol abuse: risking their health by keeping other medical providers in the dark about their substance abuse treatment? Or risking their jobs, homes, and child custody arrangements by allowing potentially damaging treatment details to be electronically shared among an array of medical providers? Advocates have painted the possible patien
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ConclusionsBecause blackouts indicate drinking at levels that result in significant cognitive and behavioral impairment, questions about blackouts could serve as important, simple screeners for the risk of experiencing other alcohol related harms. Additional work on this subject is warranted.
In 2012 to 2013, 68% (1,463/2,140) of respondents nationwide 1 year past high school reported consuming
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ConclusionsThese findings suggest that GIRK3 plays a role in EtOH reward. Furthermore, the selectivity of this effect suggests that GIRK channels could be an effective therapeutic target for the prevention and/or treatment of alcoholism.
GIRK channels are emerging as an important neural target of alcohol. Here, we investigate the role of the GIRK3 subunit in ethanol reward using conditioned place
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